Library
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2025
Best L, Dost T, Esser D, Flor S, Gamarra AM, Haase M, Kadibalban AS, Marinos G, Walker A, Zimmermann J, Simon R, Schmidt S, Taubenheim J, Künzel S, Häsler R, Franzenburg S, Groth M, Waschina S, Rosenstiel P, Sommer F, Witte OW, Schmitt-Kopplin P, Baines JF, Frahm C, Kaleta C. (2025) Metabolic modelling reveals the aging-associated decline of host–microbiome metabolic interactions in mice.External link Nat Microbiol, 10(4):973-991
Olecka M, Morrison H, Hoffmann S. (2025) Signatures of Nonlinear Aging: Molecular Stages of Life.External link Bioessays, 0:e202400222
Weber SLK, Heinzel T, Iyer-Bierhoff A. (2025) Protocol for ecotropic pseudotyped lentiviral transduction of "murinized" human cells while decreasing risk of infection for laboratory personnel.External link STAR Protoc, 6(2):103708
Simon R, Lossow K, Pellowski D, Kipp K, Achatz M, Klasen N, Schwerdtle T, Dawczynski, Kipp AP. (2025) Improving the selenium supply of vegans and omnivores with Brazil nut butter compared to a dietary supplement in a randomized controlled trial.External link Eur J Nutr, 64(2):74
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2024
Schwarz M, Kipp AP. (2024) PRDX6 as an additional piece in the puzzle of selenoprotein synthesis.External link Mol Cell, 84(23):4475-4477
Scherag A, Thomas D, Bickeböller H. (2024) Statistical Methods in Genetic Epidemiology.External link In Handbook of Epidemiology, Springer, New York.
Kalc P, Hoffstaedter F, Luders E, Gaser C, Dahnke R. (2024) Approximation of bone mineral density and subcutaneous adiposity using T1-weighted images of the human head.External link Imaging Neuroscience, 2
Stein G, Aly JS, Lange L, Manzolillo A, Riege K, Brancato A, Hübner CA, Turecki G, Hoffmann S, Engmann O. (2024) Npbwr1 signaling mediates fast antidepressant action.External link Mol Psychiatry
Löser A, Schwarz M, Kipp AP. (2024) NRF2 and thioredoxin reductase 1 as modulators of interactions between zinc and selenium.External link Antioxidants (Basel), 13(10):1211
Gaser C, Dahnke R, Thompson PM, Kurth F, Luders E, The Alzheimer's Disease Neuroimaging Initiative (2024). CAT: a computational anatomy toolbox for the analysis of structural MRI data.External link Gigascience, 13:giae049
Gaser C, Kalc P, Cole JH. (2024) A perspective on brain-age estimation and its clinical promise.External link Nat Comput Sci, 4(10):744-751
Stein G, Aly JS, Manzolillo A, Lange L, Riege K, Hussain I, Heller EA, Cubillos S, Ernst T, Hübner CA, Turecki G, Hoffmann S, Engmann O. (2024) Transthyretin orchestrates vitamin B12-induced stress resilienceExternal link. Biol Psychiatry, S0006-3223(24)01457-4
Olecka M, Bömmel van A, Haase M, Foerste S, Riege K, Dost T, Flor S, Witte OW, Franzenburg S, Groth M, Eyss von B, Kaleta C, Frahm C, Hoffmann S. (2024) Nonlinear DNA methylation trajectories in aging male miceExternal link. Nat Commun (15)1:3074
Sharifi S, Chaudhari P, Martirosyan A, Eberhardt AO, Witt F, Gollowitzer A, Lange L, Woitzat Y, Okoli EM, Li H, Rahnis N, Kirkpatrick J, Werz O, Ori A, Koeberle A, Bierhoff H, Ermolaeva M. (2024) Reducing the metabolic burden of rRNA synthesis promotes healthy longevity in Caenorhabditis elegans. External link Nat Commun (15)1:1702
Kalc P, Dahnke R, Hoffstaedter F, Gaser C. (2024) BrainAGE: Revisited and reframed machine learning workflow.External link Hum Brain Mapp 45(3):e26632
Iyer-Bierhoff A, Wieczorek M, Peter SM, Ward D, Bens M, Vettorazzi S, Guehrs KH, Tuckermann JP, Heinzel T. (2024) Acetylation-induced proteasomal degradation of the activated glucocorticoid receptor limits hormonal signaling.External link iScience, 108943
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2023
Kalc P, Dahnke R, Hoffstaedter F, Gaser C. (2023) Low bone mineral density is associated with gray matter volume decrease in UK biobank.External link Front Aging Neurosci 15
Rothermund K, Englert C, Gerstorf D. (2023) Explaining variation in individual aging, its sources, and consequences: A comprehensive conceptual model of human aging.External link Gerontology 1
Schädel P, Wichmann-Costaganna M, Czapka A, Gebert N, Ori A, Werz O. (2023) Short-term caloric restriction and subsequent re-feeding compromise liver health and associated lipid mediator signaling in aged mice.External link Nutrients 15(16):3660
Rao Z, Brunner E, Giszas B, Iyer-Bierhoff A, Gerstmeier J, Börner F, Jordan PM, Pace S, Meyer KPL, Horfstetter RK, Merk D, Paulenz C, Heinzel T, Grunert PC, Stallmach A, Serhan CN, Werner M, Werz O. (2023) Glucocorticoids regulate lipid mediator networks by reciprocal modulation of 15-lipoxygenase isoforms affecting inflammation resolution.External link PNAS 120(35) e2302070120
Garo-Pascual M, Gaser C, Zhang L, Tohka J, Medina M, Strange BA. (2023) Brain structure and phenotypic profile of superagers compared with age-matched older adults: a longitudinal analysis from the Vallecas Project.External link Lancet Healthy Longev S2666-7568(23)00079-X
Schwarz M, Meyer CE, Löser A, Lossow K, Hackler J, Ott C, Jäger S, Mohr I, Eklund EE, Patel AHA, Gul N, Alvarez S, Altinonder I, Wiel C, Maares M, Haase H, Härtlova A, Grune T, Schulze MB, Schwerdtle T, Merle U, Zischka H, Sayin VI, Schomburg L, Kipp AP. (2023) Excessive copper impairs intrahepatocyte trafficking and secretion of selenoprotein P.External link Nat Commun 14(1):3479
Schädel P, Czapka A, Gebert N, Ori A, Werz O. (2023) Metabololipidomic and proteomic profiling reveals aberrant macrophage activation and interrelated immunomodulatory mediator release during aging.External link Aging Cell e13856
Krug J, Perner B, Albertz C, Mörl H, Hopfenmüller VL, Englert C. (2023) Generation of a transparent killifish line through multiplex CRISPR/Cas9 mediated gene inactivation.External link eLife 12:e81549
Schwarz M, Löser A, Cheng Q, Wichmann-Costaganna M, Schädel P, Werz O, Arnér ES, Kipp AP. (2023) Side-by-side comparison of recombinant human glutathione peroxidases identifies overlapping substrate specificities for soluble hydroperoxides.External link Redox Biol. 59: 102593
Gull S, Gaser C, Herrmann K-H, Urbach A, Boehme M, Afzal S, Reichenbach JR, Witte OW, Schmidt S. (2023) Brain macro-structural alterations in aging rats: A longitudinal lifetime approach. External linkCells 12(3):432
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2022
Franzka P, Turecki G, Cubillos S, Kentache T, Steiner J, Walter M, Hübner CA, Engmann O (2022) Altered mannose metabolism in chronic stress and depression is rapidly reversed by vitamin B12.External link Front Nutr 9:951511
Schmidt S, Haase M, Best L, Groth M, Lindner J, Witte OW, Kaleta C, Frahm C. (2022) Restoring age-related cognitive decline through environmental enrichment: A transcriptomic approach.External link Cells 11(23): 3864
Cubillos S, Engmann O, Brancato A. (2022) BDNF as a mediator of antidepressant response: Recent advances and lifestyle interactions.External link Int J Mol Sci 23(22):14445
Ederer ML, Günther M, Best L, Lindner J, Kaleta C, Witte OW, Simon R, Frahm C. (2022) Voluntary Wheel Running in Old C57BL/6 Mice Reduces Age-Related Inflammation in the Colon but Not in the Brain.External link Cells 11(3): 566
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2021
Wolfram T, Weidenbach LM, Adolf J, Schwarz M, Schädel P, Gollowitzer A, Werz O, Koeberle A, Kipp AP, Koeberle SC. (2021) The trace element selenium is important for redox signaling in phorbol ester-differentiated THP-1 macrophages.External link Int J Mol Sci 22(20):11060